Creating New Antibiotics and Testing Natural Remedies
Time: 1:00 - 1:25 PM EST
Location: University Hall 2-048 and Zoom –– Join virtual session
Lesley Graduating Students Savannah Gravitt, Allison Eckard, Elizabeth Komar, and Caden Shott; UMASS-Boston Graduating Student Jack Labrecque; and community member Ivan Labrecque (Presenters will be in person)
Instructor: Nataliya Ryzhenko, Liberal Arts and Business / Natural Sciences and Mathematics
In this project, students explored two ways to fight bacterial resistance: synthesizing new antibiotics and testing traditional natural remedies. First, we screened a library of chemical mixtures against E. coli using the Kirby-Bauer well-diffusion test. By measuring clear zones of inhibition on agar plates, we successfully identified and verified a lead candidate.
Next, we applied these same methods to evaluate natural compounds as potential antibiotic medicines. We isolated a wild, environmentally sourced bacterial strain and tested natural remedies such as garlic, onion, cinnamon, and honey. Our presentation will compare the quantitative results—specifically the inhibition zone sizes. By doing so, we aim to demonstrate multiple viable pathways for discovering new treatments against antibiotic resistant bacteria.
The Science of Potato Defense
Time: 1:25 - 1:50 PM EST
Location: University Hall 2-048 and Zoom –– Join virtual session
Lesley Graduating Students Elizabeth Komar, Savannah Gravitt, Allison Eckard, and Caden Shott; UMass Boston-Graduating Student Jack Labrecque; and community members Ivan Labrecque and Olena Labrecque (Presenters will be in person)
Instructor: Nataliya Ryzhenko, Liberal Arts and Business / Natural Sciences and Mathematics
Why do potatoes turn brown after being sliced? This process, called enzymatic browning, is a sophisticated natural defense mechanism. When a potato is damaged, an enzyme called tyrosinase reacts with oxygen to produce melanin, the pigment coloring our skin, to create a protective barrier against insects and disease. Our study compared the defensive strength of four potato varieties: Red Pontiac, Golden Yukon, Purple Majesty, and Russet. We measured how quickly each variety produced melanin using visual timing and chemical analysis. We discovered the Golden Yukon exhibited the highest tyrosinase activity. This suggests it is naturally more resilient against environmental threats. Understanding these biochemical traits helps identify robust crops, providing valuable insights for both local gardeners and large-scale agriculture. Beyond agriculture, this research presents a unique opportunity to intersect science with art. We plan to turn our science project into art by writing a great tale about the Golden Yukon’s strength.
Material and Design Innovations in Soft Robotics
Time: 1:50 - 2:15 PM EST
Location: University Hall 2-048 and Zoom –– Join virtual session
Lesley Graduating Students Savannah Gravitt, Allison Eckard, Elizabeth Komar, Caden Shott; Lumen Academy Students Anna Labrecque; UMass, Biochemistry and Psychology Graduate Derek Ho; UMass Boston Graduating Student Jack Labrecque (Presenters will be in person)
Instructor: Nataliya Ryzhenko, Liberal Arts and Business / Natural Sciences and Mathematics
This interdisciplinary project explores the creation and practical application of soft robotic actuators. Led by chemistry and mathematics students, the team will evaluate three hyperelastic materials: platinum-cure silicones, ultra-soft thermoplastic elastomers, and edible gelatin-glycerin biopolymers.
Moving beyond basic formulation, students will cast these materials into custom 3D-printed molds. They will test how distinct morphologies dictate real-world performance by quantifying parameters such as maximum stretch, fatigue resistance, pneumatic bending angles, and seal integrity.
Furthermore, a mathematical modeling component will utilize non-linear material models to predict how these structures deform under varied pressures. By bridging theoretical math with empirical hands-on testing, this research aims to optimize soft robots for medical science, advancing high-impact applications like minimally invasive surgical tools, wearable physical therapy devices, and biodegradable ingestible robotics.